I have a question regarding the use of this software for analysis of tissue samples. I have brains that have been fluorescently labeled with an antibody that detects hyperphosphorylated tau, and I was wondering if I could use Cell Profiler to quantify the Neurofibrillary Tangles?
We will be adding in neurite detection algorithms into CellProfiler. Currently, we do not have anything that can best distinguish neurons if they are overlapping each other. Depending on the image, we might be able to help you with the current modules that are available. Please upload a few images to a publicly available site (like Picaseweb, etc) and let us know where we can find the images.