Dear Qupath users and developers,
I am a complete beginner at both pathology and image analysis, so I’m very sorry for posting a very basic question.
I am now trying to quantify “necrotic regions” on H&E-stained tumor tissue slides deposited in TCGA.
(I want to evaluate the relationship between the degree of tumor tissue necrosis and their clinical outcomes, various molecular traits, and so on.)
My questions are ;
Is QuPath suitable for my experimental purpose?
Is QuPath capable of morphologically distinguish necrotic area from others (e.g. normal cancer cells and tumor stroma)?
Is a process of training an image classifier required?
These may be silly questions, but I would appreciate it if you could give me some information or advice.