Postdoctoral Fellow Position – Image Bioinformatics - NCI/NIH


#1

The National Cancer Institute (NCI) High-Throughput Imaging Facility (HiTIF) at NIH has an open position for a Postdoctoral Fellow specialized in Image Bioinformatics to work on a variety of projects related to High-Throughput Imaging (HTI).

The successful candidate will hold a Ph.D. degree in either Image Processing, Computer Vision, Biomedical Engineering, or Quantitative Biophotonics. He/she will drive the development and implementation of automated image and data processing workflows to analyze large image datasets generated by high-throughput confocal microscopes. His/her project(s) will involve researching innovative approaches for segmenting (sub) cellular structures from multi-dimensional optical images using state-of-the art techniques (deep learning algorithms and graph-cuts), multi-modal image registration, feature extraction and unsupervised classification of phenotypic high-content/high-throughput imaging-based screens, and spatio-temporal analysis of single-cell level data. The postdoctoral fellow will work in a fast-paced research environment, will collaborate on a daily basis with cell and molecular biologists, and is expected to demonstrate independent thinking. While previous knowledge of molecular and cell biology is not a strict requirement, an interest in learning about these disciplines and in solving a variety of biological problems is essential.

The NCI HiTIF is a shared resource for NCI and NIH Investigators. We work with them in a collaborative fashion to design and execute novel high-throughput, fluorescence microscopy-based imaging assays, which are used to identify and dissect the molecular mechanisms underlying a variety of physiological and pathological cellular processes. We are based at the NIH Campus in Bethesda, the largest biomedical research institution in the world, which provides an international and vibrant environment for both basic and applied biomedical research. More importantly, we have a demonstrated successful record in developing cutting edge computational workflows on high-performance CPU and GPU batch clusters (Biowulf, CIT, NIH) to study a variety of biological pathways involved in genome architecture, chromatin regulation, the DNA Damage Response, cancer and aging, among others.

To apply, please send a cover letter and a CV to the HiTIF Director, (gianluca.pegoraro@nih.gov).