How to process a lot of images

Hi all,

I am trying to process a significant number of images…in the 10,000 range…
The two main problems are, of course, time and memory…Eventually even a single plate processing will have to be split apart, due to memory constraints (384 wells x ~500 objects etc…)
What is the best way to approach the problem? (I do not have a cluster available…maybe virtual machines?)
Thanks a lot in advance,