I have used cellprofiler and cellprofiler analyst for some time on an old macbook and generally been very happy with it. Last week I bought a new Mac with the new arm-based architecture and ran into major issues with compatibility (perhaps unsurprisingly…). I cannot get CPA running whatsoever and cellprofiler runs at crawling speed (around 10 times slower than dual core MBP from 2012 when running same images through same pipeline).
Regarding CPA, I installed the appropriate JDK (8) from Azul (https://www.azul.com/downloads/zulu-community/?package=jdk) that is developed for cross-compatibility between x86 and apple silicon arm-based architecture. Cannot start the program at all and the issue seems to be localised to the java python bridge according to the error messages in terminal. I unfortunately do not have the programming skills to address this. Regarding cellprofiler (v4.0.7) proper, everything seems functionally intact, however processing speed is unbearably slow. I really don’t know what could be done to address that.
Has anyone here experienced or solved these issues?