I am wondering if there is a way to get ImageJ to automatically count cells based on whether signals from 2 channels are present? I am trying to count oligodendrocytes and have DAPI and p25a as markers. I want to be able to count only the particles which show both signals as the image contains different combinations of these. I was thinking maybe a mask of one channel overlaid on the other could work but I am not sure if this is possible. I would appreciate any suggestions. Thank you!